Oklahoma at Georgia and Oregon at USC lead the opening Week 4 college football odds. The Bulldogs are laying 14 points in Athens, while the Trojans are just 1.5-point favorites in a game with a 62.5 total.

Texas visits Tennessee, LSU hosts Texas A&M, and Ole Miss heads to Florida after its win over the Tigers. The early board also includes Friday’s Northwestern–Indiana game and a low-total Big Ten matchup between Iowa and Michigan.

The table below covers all 20 games currently listed at DraftKings, with one row per matchup. Compare these early prices with the live college football odds as the week develops.

Early Week 4 odds from DraftKings as of Sep. 20; away team listed first. For sportsbook offers, see the current BetMGM promo code .

Oregon vs USC has the highest total on the early Week 4 board at 62.5, with the Trojans favored by just 1.5. Iowa vs Michigan sits at the opposite extreme with a 37.5 total, while Miami’s 42.5-point spread against Central Michigan is the largest.

Georgia is laying two touchdowns against Oklahoma, and Texas is a 5.5-point road favorite at Tennessee. Ole Miss–Florida and Oklahoma State–West Virginia join Oregon–USC among the tightest lines at 1.5 points.

Those close games are worth a price comparison on prediction market apps . Check available contracts at Kalshi and Polymarket before choosing where to take your side, comparing the same outcome and accounting for fees.

Georgia hosts Oklahoma at 3:30 pm ET Saturday on ABC. The 14-point spread leaves a push if the Bulldogs win by exactly two touchdowns, while the 47.5 total implies roughly 31 points for Georgia and 17 for Oklahoma.