Week 3 of the 2026 NFL season is underway after a Thursday night clash where the Atlanta Falcons secured a decisive 35-14 road victory over the Green Bay Packers, pulling away with 28 points across the final three quarters. I won with Falcons +5.5 against the Packers on Thursday night, so I am looking to keep the momentum going.

We now turn our attention to the Sunday slate, featuring nine games starting at 1:00 PM ET. The schedule highlights pivotal early-season matchups, including an AFC South clash where the Houston Texans visit the Indianapolis Colts, and an inter-conference battle between the Saints and the surprisingly 2-0 Raiders, both of which will be discussed later in my best bets for the week. Week 3 concludes Monday night, when the Chicago Bears host the 2-0 Philadelphia Eagles, who sit first in the NFC East.

Below, you will find spreads and an against-the-spread pick for every remaining game, factoring in early NFL ATS records alongside a detailed breakdown of my four best bets.

Spreads are sourced from BetMGM and are current as of publication. Claim your BetMGM promo now .

This week’s top NFL against-the-spread plays highlight four squads primed to cover in their matchups. Some might look gross, but hear me out.

To kick off this week’s betting card, I am backing the Washington Commanders to cover against the Seattle Seahawks. I know it is Marcus Mariota, but he has been serviceable when he has gotten starts these last couple of years. We are getting a full touchdown with the home team, and I think they can surprise NFL fans everywhere, making this a close game against the defending champs.

Since 2022, NFL teams that are 0-2 are 19-9 against the spread in Week 3 when facing a team with at least one. That helped me win the Falcons on TNF, and I am going back to it here, no matter how ugly this pick looks. The Seahawks have a strong front seven, and Washington’s offensive line is less than ideal, but Mariota has seen success scrambling and putting up points against these types of defenses. By staying ahead of the chains, the Commanders keep their defense fresh and heavily limit the opposing total snap count. Seattle relies on explosive downfield passing, which becomes increasingly difficult when your offense spends long stretches watching from the sideline.

NFL Week 3 Pick: Commanders +7.5 (-110)